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Global Health Lab

Q-Plex Multiplexed Assay

A multiplexed diagnostic platform applied to address varied global health challenges
Country: usa
Contact Person: Nicole Hawkes




PATH has partnered with Quansys Biosciences to apply the Q-Plex multiplexed diagnostics platform to address varied global health challenges. For example, PATH, the University of Washington, and Quansys Biosciences developed the Q-Plex™ Human Micronutrient Array (7-plex), which simultaneously quantifies vitamin A, iron, and iodine deficiency biomarkers, as well as inflammation and Plasmodium falciparum malaria, using just a single sample.

This multiplexing technology enables researchers to obtain more information in less time and at lower cost for community surveillance. Additionally, the Q-Plex™ Human Malaria Array measures histidine rich protein 2 (HRP2) and plasmodium lactate dehydrogenase (pLDH) at low concentrations, as well as quantify Plasmodium vivax- and Plasmodium falciparum-specific LDH epitopes to distinguish between malaria species and C-reactive protein (CRP) as an indicator of inflammation.

Researchers can use the Q-Plex™ Human Malaria Array (5-Plex) as a reference test to evaluate rapid diagnostic tests(RDTs) in the development pipeline that detect malaria infections with low parasite concentrations and address the challenge of diagnosing P. falciparum malaria parasite strains that do not produce HRP2 and therefore are not detected by RDTs designed to identify the antigen.






Level of development:
  • Marketed with well-documented field experience


QPlex 02   qplex01   QPlex 04



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